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Vol. 24. Issue 1.
Pages 54-60 (01 January 2020)
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Vol. 24. Issue 1.
Pages 54-60 (01 January 2020)
Original Research
DOI: 10.1016/j.bjpt.2018.11.009
The minimal important difference for Glittre-ADL test in patients with chronic obstructive pulmonary disease
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Aline Almeida Gularta,b, Cintia Laura Pereira de Araujoc,d, Anelise Bauer Munaria,b, Karoliny dos Santosa, Manuela Karloha,e, Betina Gabriele Foscarinic, Pedro Dal Lagoc,d, Anamaria Fleig Mayera,b,e,
Corresponding author
anamaria.mayer@udesc.br

Corresponding author at: Núcleo de Assistência, Ensino e Pesquisa em Reabilitação Pulmonar, UDESC, Rua Pascoal Simone 358, CEP 88080-350, Florianópolis, SC, Brazil.
a Center for Assistance, Teaching and Research in Pulmonary Rehabilitation (NuReab), Universidade do Estado de Santa Catarina (UDESC), Florianópolis, SC, Brazil
b Human Movement Sciences Graduate Program, Centro de Ciências da Saúde e do Esporte (CEFID), Universidade do Estado de Santa Catarina (UDESC), Florianópolis, SC, Brazil
c Research Group on Cardiopulmonary Interaction (GPIC), Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil
d Health Sciences Graduate Program, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil
e Physical Therapy Graduate Program, Centro de Ciências da Saúde e do Esporte (CEFID), Universidade do Estado de Santa Catarina (UDESC), Florianópolis, SC, Brazil
Highlights

  • Glittre-ADL test minimal important difference (MID) is −0.38min in COPD patients.

  • Glittre-ADL test's MID reflects the changes in functional capacity.

  • Two tests are necessary for interpretation of changes induced by pulmonary rehabilitation.

Article information
Abstract
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Tables (3)
Table 1. Distribution-based estimates of the minimal important difference (MID) and results.
Table 2. Anthropometric characteristics and pulmonary function of the sample.
Table 3. Functional capacity improvement.
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Abstract
Objective

To determine Glittre-ADL test minimal important difference in patients with chronic obstructive pulmonary disease.

Methods

This is quasi-experimental study. Sixty patients with moderate to very severe chronic obstructive pulmonary disease (age 64.1, SD=9.09 years; forced expiratory volume in the first second 37.9, SD=13.0% predicted participated in a pulmonary rehabilitation program based on physical training, conducted over 24 sessions supervised, three times a week, including aerobic training in treadmill and resistance training for upper limbs and lower limbs. The main outcomes were the Glittre-ADL test and six-minute walk test, before and after 24 sessions of pulmonary rehabilitation. The minimal important difference was established using the distribution and anchor-based methods.

Results

Patients improved their functional capacity after the pulmonary rehabilitation. The effect sizes of Glittre-ADL test and six-minute walk test improvement were similar (0.45 vs 0.44, respectively). The established minimal important differences ranged from −0.38 to −1.05. The reduction of 0.38min (23s) corresponded to a sensitivity of 64% and a specificity of 69% with an area under the curve of 0.66 (95%CI 0.51–0.81; p=0.04). Subjects who achieved the minimal important difference of −0.38min for the Glittre-ADL test had a superior improvement of approximately 42m in the six-minute walk test when compared to patients who did not.

Conclusions

The present findings suggest −0.38min as the minimal important difference in the time spent in the Glittre-ADL test after 24 sessions of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease.

Trial registration: NCT03251781 (https://clinicaltrials.gov/ct2/show/NCT03251781)

Keywords:
Pulmonary disease
Chronic obstructive
Rehabilitation
Activities of daily living
Exercise test
Outcome assessment

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