Publish in this journal
Journal Information
Vol. 21. Issue 4.
Pages 296-304 (01 July 2017)
Download PDF
More article options
Vol. 21. Issue 4.
Pages 296-304 (01 July 2017)
Original Research
DOI: 10.1016/j.bjpt.2017.05.010
Effect of low-level laser therapy (LLLT) and light-emitting diodes (LEDT) applied during combined training on performance and post-exercise recovery: protocol for a randomized placebo-controlled trial
Aryane Flauzino Machadoa, Jéssica Kirsch Michelettia, Franciele Marques Vanderleia, Fabio Yuzo Nakamurab, Ernesto Cesar Pinto Leal-Juniorc, Jayme Netto Juniora, Carlos Marcelo Pastrea,
Corresponding author

Corresponding author at: Rua Roberto Simonsen, 305 – Presidente Prudente/São Paulo 19060-900, Brazil.
a Postgraduate Program in Physical Therapy, Universidade Estadual Paulista (UNESP), Presidente Prudente, SP, Brazil
b Nucleus of High Performance in Sport, São Paulo, SP, Brazil
c Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil

  • This is a high quality randomized controlled trial (with blinded assessors).

  • This is the first trial to adjust phototherapy to training after control of the primary adaptation process.

  • The intervention under investigation may reflect the real effect of phototherapy.

This item has received
Article information
Full Text
Download PDF
Figures (1)
Tables (3)
Table 1. Training program.
Table 2. Phototherapy parameters.
Table 3. Time point of outcomes.
Show moreShow less

Previous studies have shown positive results of phototherapy for improving performance and accelerating recovery; however, the effects of phototherapy during training and after a primary adaptation remain unclear. The aim of this randomized controlled trial is to analyze the effects of phototherapy and combined training on clinical, functional, and psychological outcomes and on vascular endothelial growth factor.


This randomized placebo-controlled trial by stratified sample will involve 45 healthy male participants. In phase 1, the participants will undergo six weeks of combined training (sprints and squats). In phase 2, participants will be allocated through stratified randomization (based on adaptation capacity) into three groups: active phototherapy group (AG), placebo group (PG), and non-treatment control group (CG). A new six-week training program will then start and the participants will receive the recovery strategy between sprints and squats. The primary outcome will be maximal isometric contraction. The secondary outcomes include strength and power testing, maximal incremental test, squat jump, sprint test, muscle soreness, pain threshold, perceptions of exertion and recovery, psychological questionnaire, and vascular endothelial growth factor.


This will be the first trial to include phototherapy during training. We believe that this strategy will combine the ergogenic and prophylactic effects in the same session. Furthermore, an application protocol performed after primary adaptation may reflect the real effect of the technique.

Recovery of function
Athletic performance


These are the options to access the full texts of the publication Brazilian Journal of Physical Therapy

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Brazilian Journal of Physical Therapy

Subscribe to our newsletter

Article options
en pt
Cookies policy Política de cookies
To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.